DANIEL J. HOARD
SAINT LOUIS UNIVERSITY
Webster Groves
8
years of professional experience
Research Professional experienced in experimental design and data interpretation. Contributed to impactful studies through collaboration and advanced analytical techniques, delivering thorough and accurate research outcomes. Focused on driving research initiatives forward within multidisciplinary teams.
Work History
GRADUATE RESEARCHER
6 Years 3 Months- Conducted research in carbohydrate synthesis at Dr. Alexei Demchenko's laboratory
- Developed and tested a novel approach for synthesizing glycosyl chlorides from thioglycosides, enhancing reaction efficiency
- Investigated unique reactivity of galactosyl halides, revealing conditions that reverse reactivity trends
- Development of synthetic pathways for target structures
- Purification and Identification of organic compounds
- Trained laboratory personnel on safe operation of new equipment, ensuring compliance with safety protocols
- Managed the maintenance of critical equipment
- Presented my research internationally at EuroCarb 22 in Gdańsk, Poland
Researcher under Dr. Keith Stein
5 Months- Formulated pharmaceutical delivery systems utilizing gold nanoparticles targeting cancer treatments
- Tested and analyzed chemical processes, collaborating with team to enhance laboratory outcomes.
- Investigated process impurities affecting compound reproducibility, leading to updated cleaning procedures that mitigated issue recurrence.
Researcher under Dr. Alexei Demchenko
4 Months- Received the "Glycoworld Distinguished Award" for synthesizing unpublished compounds.
- Preformed organic manipulation techniques to form compounds such as “3,4,6-Tri-O-benzoyl-2-deoxy-2-phthalimido- β-D-glucopyranosyl Chloride”.
- Conducted carbohydrate synthesis experiments using wet-lab techniques, maintaining strict protocol adherence and reproducibility.
- Optimized reaction conditions to improve product purity, yield consistency, and downstream analysis accuracy.
- Characterized compounds using NMR, HPLC, and mass spectrometry, documenting results in detailed laboratory records.
Education
Doctor of Philosophy - Chemistry
Dissertation: Synthesis and Reactivity of Galactosyl Chlorides
Bachelor of Science - Chemistry
Skills
C¹³ and H¹ NMR
Mass Spectroscopy
Atomic Emission Spectroscopy
DEPT
COSY
HSQC
Liquid / Gas Chromatography
TLC Analysis
Crystallography
Electron Microscopy
Infrared Spectroscopy
Detailed Laboratory Note Taking
Device Training
Equipment/Device Maintenance
Project Management
Inventory Management
Software: MS Office
MS Windows
MestReNova
ChemDraw
Rotary Evaporator
PUBLICATIONS
- P1. “A highly efficient glycosidation of glycosyl chlorides using cooperative silver(I) oxide - triflic acid catalysis”, Geringer, S. A.; Singh, Y.; Hoard, D. J.; Demchenko, A. V. Chem. Eur. J. 2020, 26, 8053-8063.
- P2. “Synthesis of Orthogonally Protected p-Tolyl 2-azido-3-O-benzyl-6-O-tert-butyldiphenylsilyl-2-deoxy-4-O-levulinoyl-1-thio-β-D-glucopyranoside”, I. Ponger, D. Hoard and G. J. Miller. Carbohydrate Chemistry: Proven Synthetic Methods, 6, 2025.
- P3. “Direct Synthesis of Glycosyl Chlorides from Thioglycosides”, Hoard, D. J.; Sutar, Y.; Demchenko, A. V. J. Org. Chem. 2024, 89 (10), 6865-6876.
- P4. “Differentially Substituted Galactosyl Chlorides Reveal Unusual Reactivity Trends under the 4K Reaction Conditions”, Hoard, D. J. Sutar, Y.; Demchenko, A. V. J. Org. Chem. 2025, 90 (45), 16121-16130.
Timeline
GRADUATE RESEARCHER
SAINT LOUIS UNIVERSITY
05.2020 - 08.2026Read More
Researcher under Dr. Keith Stein
NANOPARTICLE RESEARCH LABORATORY (UMSL)
08.2019 - 01.2020Read More
Researcher under Dr. Alexei Demchenko
CARBOHYDRATE SYNTHESIS LABORATORY (UMSL)
01.2019 - 05.2019Read More
UNIVERSITY OF MISSOURI – SAINT LOUIS
Bachelor of Science from Chemistry
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SAINT LOUIS UNIVERSITY
Doctor of Philosophy from Chemistry
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